Endocrine-Disrupting Chemicals

From Basic Research to Clinical Practice
 Buch
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ISBN-13:
9781588298300
Einband:
Buch
Erscheinungsdatum:
01.07.2007
Seiten:
361
Autor:
Andrea C. Gore
Gewicht:
934 g
Format:
256x152x26 mm
Serie:
Contemporary Endocrinology
Sprache:
Englisch
Beschreibung:

Strong evidence for effects of EDCs, including low-level exposures, on humans and wildlife
Contents
Preface

Contributors

Part I. The Basic Biology of Endocrine Disruption

1. Introduction to Endocrine-disrupting Chemicals
Andrea C. Gore

2. Endocrine Disruption and the Female
Ana M. Soto, Beverly S. Rubin, and Carlos Sonnenschein

3. Endocrine Disruption in the Male
Prue A. Cowin, Paul M.D. Foster, and Gail P. Risbridger

4. Endocrine Disruption and the Brain
Deena M. Walker and Andrea C. Gore

5. Heavy Metals as Endocrine-disrupting Chemicals
Cheryl A. Dyer

6. Cellular Mechanisms of Endocrine Disruption: Traditional and Novel
Actions
Stuart R. Adler

7. Endocrine Disruptors, Epigenetically Induced Changes, and
Transgenerational Transmission of Characters and Epigenetic States
Carlos Guerrero-Bosagna and Luis Valladares

Part II. The Biology of EDCs in Humans

8. Implications of Thyroid Hormone Signaling through the
Phosphoinositide-3 Kinase for Xenobiotic Disruption of Human Health
David L. Armstrong9. Endocrine Disruption and Reproductive Outcomes in Women
Sarah Janssen, Victor Y. Fujimoto, and Linda C. Giudice

10. Epidemiologic Evidence on the Relationship between Environmental
Endocrine Disruptors and Male Reproductive and Developmental Health
Russ Hauser, Julia S. Barthold, and John D. Meeker

11. Human Exposures and Body Burdens of Endocrine-disrupting Chemicals
Antonia M. Calafat and Larry L. Needham

Part III. Implications and Mitigations of EDCs

12. Policy Implications of Endocrine-disrupting Chemicals in Humans
Tracey J. Woodruff

13. Talking with Patients and the Public about Endocrine-Disrupting
Chemicals
Gina Solomon and Sarah Janssen

14. Community Interventions to Reduce Exposures to Chemicals with
Endocrine Disrupting Properties
Barbara Brenner and Maida Galvez

15. What can we do about Endocrine-Disrupting Chemicals?
Joseph Thornton
Endocrine Disrupting Chemicals: From Basic Research to Clinical Practice is the first book that provides comprehensive coverage of the three most important themes in the field of EDC research: the basic biology of EDCs, particularly their effects on reproductive systems; EDC effects on humans and wildlife, including biomedical considerations; and potential interventions and practical advice for dealing with the problem of EDCs. This book presents a translational approach to EDC research, spanning both basic biology and clinical applications, and provides a critical link between the laboratory and the physicians office. Scientists and physicians engaged in EDC studies or practice will find that this volume offers insight across all areas of EDC research, including clarifying the mechanisms for EDC effects, understanding the adverse affects of EDCs on humans and wildlife, and offering solutions to the problems created by exposures to EDCs.

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