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Foreword by Maik Gollasch.- Editorial, Andre Kamkin and Ilya Lozinsky.- Contributors.- 1 Force from lipids: A multidisciplinary approach to study bacterial mechanosensitive ion channels, Charles G. Cranfield et al.- 2 Mechanosensitive K2P channels, TREKking through the autonomic nervous system,.J. Antonio Lamas.- 3 TRPV1 in cell signaling: molecular mechanisms of function and modulation, Andrés Jara-Oseguera and Tamara Rosenbaum.- 4 The Molecular Mechanism of Multifunctional Mechano-Gated Channel TRPV4, Makoto Suzuki and Astuko Mizuno.- 5 Mechanical stretch and intermediate-conductance Ca2+-activated K+ channels in arterial smooth muscle cells, Yasunobu Hayabuchi et al.- 6 Sensing mechanism of stretch activated ion channels, Naomi Niisato and Yoshinori Marunaka.- 7 Ion channels in cardiac fibroblasts: Link to mechanically gated channels and their regulation, Denis V. Abramochkin, Ilya Lozinsky, and Andre Kamkin.- 8 The role of nitric oxide in the regulation of ion channels in the cardiomyocytes: Link to mechanically gated channels, Ekaterina Yu. Makarenko, Ilya Lozinsky, Andre Kamkin.- 9 The Role of Ion Channels in Cellular Mechanotransduction of Hydrostatic Pressure, Kevin D. Champaigne and Jiro Nagatomi.- 10 Lipid-mediated mechanisms involved in the mechanical activation of TRPC6 and TRPV4 channels in the vascular tone regulation, Ryuji Inoue et al.- 11 Stretch effects on atrial conduction: a potential contributor to arrhythmogenesis, Michela Masè and Flavia Ravelli.- 12 Early activation of intracellular signals after myocardial stretch, Horacio E. Cingolani et al.- 13 Recent aspects of angiotensin II action in the heart. Implications for myocardial ischemia and heart failure, Walmor C De Mello.- 14 Mechanosensitivity of pancreatic beta-cells, adipocytes, and skeletal muscle cells: the therapeutic targets of metabolic syndrome, Koichi Nakayama et al.- 15 The role of the primary cilium in chondrocyte response tomechanical loading, Angus KT Wann, CL Thompson, and Martin M Knight.- Index